SCHEMBL27985773

SCHEMBL27985773

CCn1c(-c2ccccc2-n2c3ccccc3c3ccccc32)nc2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 14/20 0.51
ALDH1A1 P00352 13/20 0.51
HPGD P15428 10/20 0.51
MAPT P10636 8/20 0.50
HTT P42858 7/20 0.50
HSD17B10 Q99714 7/20 0.50
TP53 P04637 2/20 0.50
RCE1 Q9Y256 1/20 0.50
NPSR1 Q6W5P4 6/20 0.49
NPC1 O15118 3/20 0.49
KMT2A Q03164 3/20 0.49
CYP1A2 P05177 2/20 0.49
MEN1 O00255 2/20 0.49
RAB9A P51151 2/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
GFER P55789 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CYP2D6 P10635 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231419 0.83 KDM4E (0.64) KDM4EALDH1A1HPGDMAPTHTT
SCHEMBL4017475 0.82 ALDH1A1 (0.62) KDM4EALDH1A1HPGDMAPTHTT
SCHEMBL230641 0.78 ALDH1A1 (0.70) KDM4EALDH1A1HPGDMAPTHTT
SCHEMBL18932081 0.77 RECQL (0.58) KDM4EALDH1A1HPGDMAPTHTT
SCHEMBL16692204 0.77 KDM4E (0.69) KDM4EALDH1A1HPGDMAPTHTT
SCHEMBL11522697 0.77 ALDH1A1 (0.69) KDM4EALDH1A1HPGDMAPTHTT
SCHEMBL17405258 0.76 ALDH1A1 (0.38) KDM4EALDH1A1HPGDMAPTHTT
SCHEMBL25112954 0.73 KDM4E (0.49) KDM4EALDH1A1HPGDMAPTHTT
SCHEMBL5009162 0.72 KDM4E (0.77) KDM4EALDH1A1HPGDMAPTHTT
SCHEMBL12854051 0.72 RECQL (0.56) KDM4EALDH1A1HPGDMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104513997-A 1-ethyl-2-substituted benzimidazole carbon steel pickling corrosion inhibitor and application thereof NANJING UNIVERSITY OF TECHNOLOGY 2015-04-15 CN disclosed