Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | OGG1 | O15527 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | EPM2A | O95278 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1085590 | 0.79 | CA1 (0.46) | CA1CA2CA5ACA9CYP2A6 | |
| SCHEMBL13526 | 0.79 | CA1 (0.46) | CA1CA2CA5ACA9CYP2A6 | |
| SCHEMBL756324 | 0.79 | PDE2A (0.50) | CA1CA2CA5ACA9CYP2A6 | |
| Iodide SCHEMBL25233569 | 0.77 | PDE2A (0.48) | CA1CA2CA5ACA9CYP2A6 | |
| Hydrochloric Acid SCHEMBL992228 | 0.77 | PDE2A (0.48) | CA1CA2CA5ACA9CYP2A6 | |
| SCHEMBL30504214 | 0.77 | KCNN4 (0.43) | ALDH1A1MAPK1PDE2ANOS1CES2 | |
| SCHEMBL3979356 | 0.75 | CYP2A6 (0.40) | CA1CA2CA5ACA9CYP2A6 | |
| SCHEMBL16886837 | 0.75 | CA1 (0.43) | CA1CA2CA5ACA9CYP2A6 | |
| SCHEMBL7944567 | 0.75 | CYP2A6 (0.40) | CA1CA2CA5ACA9CYP2A6 | |
| SCHEMBL1025732 | 0.75 | CYP2A6 (0.40) | CA1CA2CA5ACA9CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046179-B | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS INC | 2015-01-14 | — | — | CN | disclosed |