Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 5/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37204 | 0.98 | SMPD1 (0.42) | SMPD1LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL14841937 | 0.91 | SMPD1 (0.37) | SMPD1LPAR3LPAR1LPAR2CYP3A4 | |
| Bicarbonate SCHEMBL8377088 | 0.90 | SMPD1 (0.36) | SMPD1LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL9633573 | 0.88 | LPAR3 (0.58) | SMPD1LPAR3LPAR1LPAR2LPAR5 | |
| Triclofos SCHEMBL2864015 | 0.87 | LPAR3 (0.38) | SMPD1LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL37202 | 0.86 | CYP3A4 (0.47) | SMPD1LPAR3LPAR1LPAR2CYP3A4 | |
| SCHEMBL27661095 | 0.86 | CYP3A4 (0.44) | SMPD1LPAR3LPAR1LPAR2CYP3A4 | |
| Triphenyl Phosphate SCHEMBL28210906 | 0.82 | TSHR (0.39) | TSHR | |
| SCHEMBL4145527 | 0.78 | TSHR (0.42) | CYP3A4TSHRHPGDSMN1; SMN2CES1 | |
| SCHEMBL8380842 | 0.76 | LPAR3 (0.58) | SMPD1LPAR3LPAR1LPAR2LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101992958-B | Paper feed roller | SUMITOMO RUBBER IND | 2015-01-07 | — | — | CN | disclosed |