Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 2/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129048 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL12254198 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL12511298 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL18815074 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31217551 | 0.74 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL31217583 | 0.74 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL31217616 | 0.74 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL31217608 | 0.74 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL1336698 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL28347656 | 0.72 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1HPGDTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104114528-A | Amorphous, high glass transition temperature copolyester compositions, methods of manufacture, and articles thereof | SAUDI BASIC IND CORP | 2014-10-22 | — | — | CN | disclosed |