Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398044 | 0.90 | CNR2 (0.57) | CNR2GLAGAAMAPTLMNA | |
| SCHEMBL9310747 | 0.84 | CNR2 (0.52) | CNR2GLAMAPTCA12CA9 | |
| SCHEMBL21753821 | 0.77 | GLA (0.54) | CNR2GLAMAPTMCOLN3 | |
| SCHEMBL4075322 | 0.77 | MAPT (0.64) | CNR2MEN1KMT2AGAAMAPT | |
| SCHEMBL18591589 | 0.76 | GLA (0.59) | CNR2GLAGAAMAPTLMNA | |
| Ditolamide SCHEMBL2110790 | 0.74 | CA9 (0.64) | CNR2GLAMEN1KMT2ALMNA | |
| SCHEMBL3626535 | 0.74 | CA12 (0.50) | CNR2GLAMEN1KMT2AGAA | |
| SCHEMBL6900864 | 0.73 | HTT (0.51) | CNR2GLAMAPTLMNAALDH1A1 | |
| SCHEMBL898459 | 0.73 | GLA (0.56) | CNR2GLAGAAMAPTLMNA | |
| SCHEMBL218536 | 0.73 | SMN1; SMN2 (0.68) | CNR2GLAGAAMAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104302358-A | 3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use | CANCER RES INST ROYAL | 2015-01-21 | — | — | CN | disclosed |