SCHEMBL218536

SCHEMBL218536

Cc1ccc(S(=O)(=O)N(CCO)CCO)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.68
GLA P06280 1/20 0.56
NPC1 O15118 1/20 0.55
GAA P10253 1/20 0.55
KEAP1 Q14145 1/20 0.51
NFE2L2 Q16236 1/20 0.51
CNR2 P34972 2/20 0.51
ALDH1A1 P00352 3/20 0.51
KDM4E B2RXH2 2/20 0.51
HSD17B10 Q99714 2/20 0.51
MAPK1 P28482 1/20 0.51
MMP1 P03956 3/20 0.49
MMP7 P09237 3/20 0.49
MMP8 P22894 3/20 0.49
MMP12 P39900 3/20 0.49
MMP13 P45452 3/20 0.49
VCAM1 P19320 1/20 0.49
CA12 O43570 1/20 0.49
CA2 P00918 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15177296 0.98 SMN1; SMN2 (0.66) SMN1; SMN2GLANPC1GAAKEAP1
SCHEMBL8192690 0.98 SMN1; SMN2 (0.66) SMN1; SMN2GLANPC1GAAKEAP1
SCHEMBL12390979 0.96 SMN1; SMN2 (0.64) SMN1; SMN2GLANPC1GAAKEAP1
SCHEMBL18410344 0.92 SMN1; SMN2 (0.58) SMN1; SMN2GLANPC1GAAKEAP1
SCHEMBL12391143 0.92 SMN1; SMN2 (0.58) SMN1; SMN2GLANPC1GAACNR2
SCHEMBL8626916 0.92 SMN1; SMN2 (0.58) SMN1; SMN2GLANPC1GAACNR2
SCHEMBL14701542 0.91 SMN1; SMN2 (0.57) SMN1; SMN2GLANPC1GAAKEAP1
SCHEMBL11711049 0.91 SMN1; SMN2 (0.56) SMN1; SMN2GLANPC1GAAKEAP1
SCHEMBL2805282 0.90 SMN1; SMN2 (0.56) SMN1; SMN2GLANPC1GAAKEAP1
SCHEMBL23297778 0.85 SMN1; SMN2 (0.51) SMN1; SMN2GLANPC1GAAKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106669-B Curing agent based on N-hydroxyethyl benzene sulfonamide compound and preparation method and application thereof 镇江牛盾新材料科技有限公司 2022-08-26 CN claimed
CN-114106669-A Curing agent based on N-hydroxyethyl benzene sulfonamide compound and preparation method and application thereof 镇江牛盾新材料科技有限公司 2022-03-01 CN claimed
US-8859694-B2 Cure accelerators HEXCEL COMPOSITES LIMITED (GB) 2014-10-14 US claimed
US-8058329-B2 as flameproofing agents for polymers such as polyesters, polyamides, polycarbonates, polystyrenes, polyethylene, polypropylene, phenolic and epoxy resins Schill+Seilacher “Struktol” Aktiengesellschaft (DE) 2011-11-15 US claimed
US-20110067812-A1 CURE ACCELERATORS HEXCEL COMPOSITES LIMITED (GB) 2011-03-24 US claimed
EP-1866320-B1 NITROGEN-CONTAINING BRIDGED DERIVATIVES OF 6H-DIBENZ(E,E)(1,2)-OXAPHOSPHORINE-6-OXIDES METHOD FOR PRODUCTION AND USE THEREOF AS FLAME-RETARDANT AGENTS SCHILL & SEILACHER STRUKTOL AG (DE) 2009-02-18 EP claimed
US-20080167405-A1 Nitrous Bridged Derivatives of 6H-Dibenz[C,E][1,2]-Oxaphosphorine-6-Oxides, Process For the Preparation and Use Thereof SCHILL+SEILACHER "STRUKTOL" AKTIENGESELLSCHAFT (DE) 2008-07-10 US claimed
US-20050272883-A1 Cure accelerators HEXCEL COMPOSITES, LTD. (GB) 2005-12-08 US claimed
US-6187083-B1 INK COMPOSITION COMPRISING SELECTED INK VEHICLE, AMIDE VISCOSITY MODIFIER, CONDUCTIVE SULFONATE SALT ALL HAVING MELTING POINTS WITHIN SPECIFIED RANGE, COLORANT, OPTIONAL ANTIOXIDANT AND ULTRAVIOLET ABSORBER XEROX CORPORATION 2001-02-13 US claimed
EP-0325762-B1 Macrocyclic chelating agents and chelates thereof BRACCO SPA (IT) 1995-03-22 EP claimed
CN-120289335-A Synthesis method of sulfonamide compound 寿光诺盟化工有限公司 2025-07-11 CN disclosed
CN-114249979-B Polyamide composition with NTC effect and preparation method thereof 金发科技股份有限公司 2022-08-30 CN disclosed
CN-114106669-B Curing agent based on N-hydroxyethyl benzene sulfonamide compound and preparation method and application thereof 镇江牛盾新材料科技有限公司 2022-08-26 CN disclosed
US-20220193249-A1 Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-O-) Units In A Ring POLYTHERICS LIMITED (GB) 2022-06-23 US disclosed
CN-114249979-A Polyamide composition with NTC effect and preparation method thereof 金发科技股份有限公司 2022-03-29 CN disclosed
EP-0617028-A1 Enantiomers of 1-(4-chlorophenyl)phenylmethyl)-4-(4-methylphenyl)sulfonyl piperazine U C B, S.A. (BE) 1994-09-28 EP disclosed
US-5132409-A Derivatives of 1,4,7,10-Tetraazacyclododecane BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1992-07-21 US disclosed
US-5095044-A Odorless, discoloration inhibition CIBA-GEIGY CORPORATION (US) 1992-03-10 US disclosed
US-4950795-A PRINTING PLATES, PAPER COATING CIBA-GEIGY CORPORATION (US) 1990-08-21 US disclosed
EP-0325762-A1 Macrocyclic chelating agents and chelates thereof BRACCO S.p.A. (IT) 1989-08-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220193249-A1 Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-O-) Units In A Ring BCR, CD2BP2, LANCL1 SMN1; SMN2 3092/4885GLA 3280/4885NPC1 3200/4885
US-20080167405-A1 Nitrous Bridged Derivatives of 6H-Dibenz[C,E][1,2]-Oxaphosphorine-6-Oxides, Process For the Preparation and Use Thereof PFAS, PCBP1, DNPH1 SMN1; SMN2 1226/4885GLA 4462/4885NPC1 4032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.