Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTMT1 | Q9BV86 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27988972 | 0.93 | NOTUM (0.49) | NTMT1FFAR4NOTUM | |
| SCHEMBL27988992 | 0.86 | NOTUM (0.46) | NTMT1NOTUMDEGS1NPC1RAB9A | |
| SCHEMBL28597887 | 0.84 | NOTUM (0.43) | NTMT1FFAR4NOTUM | |
| SCHEMBL22499928 | 0.81 | NOTUM (0.53) | NTMT1NOTUMDEGS1 | |
| SCHEMBL28597269 | 0.81 | NOTUM (0.53) | NTMT1NOTUMDEGS1 | |
| SCHEMBL23500782 | 0.80 | ACACB (0.48) | FFAR4NOTUMMAPK1MAPTCHRM5 | |
| SCHEMBL28543053 | 0.79 | SLC16A3 (0.38) | NTMT1ALDH1A1L3MBTL1 | |
| SCHEMBL20484096 | 0.79 | NOTUM (0.52) | FFAR4NOTUMDEGS1MAPT | |
| SCHEMBL28603264 | 0.77 | ACACB (0.48) | NOTUM | |
| SCHEMBL27666702 | 0.75 | GFER (0.44) | NTMT1NPC1RAB9ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104203928-A | Triazinone compound and T-type calcium channel inhibitor | NISSAN CHEMICAL IND LTD | 2014-12-10 | — | — | CN | disclosed |