Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAK | O14976 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27989183 | 0.79 | NTMT1 (0.50) | ALDH1A1L3MBTL1NTMT1 | |
| SCHEMBL28597887 | 0.78 | NOTUM (0.43) | ACACBNTMT1 | |
| SCHEMBL28543055 | 0.78 | MAP4K4 (0.52) | GAK | |
| SCHEMBL28543056 | 0.78 | MAP4K4 (0.52) | GAK | |
| SCHEMBL12312211 | 0.76 | GAK (0.56) | SLC16A3SLC16A1GAKALDH1A1 | |
| SCHEMBL23243692 | 0.75 | GAK (0.47) | SLC16A3SLC16A1GAKHSD11B1ADRA1D | |
| SCHEMBL23243695 | 0.75 | GAK (0.47) | SLC16A3SLC16A1GAKHSD11B1ADRA1D | |
| SCHEMBL10207748 | 0.75 | LRRK2 (0.42) | SLC16A3SLC16A1MEN1KMT2AGAK | |
| SCHEMBL30135513 | 0.75 | LRRK2 (0.43) | MEN1KMT2AGAKALDH1A1LMNA | |
| SCHEMBL311552 | 0.75 | LRRK2 (0.43) | MEN1KMT2AGAKALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601742-A | Cathepsin C inhibitors | 北京生命科学研究所 | 2021-04-02 | — | — | CN | disclosed |