Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240482 | 0.78 | TRPV1 (0.61) | LMNAPOLBTRPV1PAX8HDAC4 | |
| Ammonia Solution, Strong SCHEMBL27989598 | 0.78 | PSMD14 (0.48) | RORCLMNAPOLBAR | |
| SCHEMBL30398203 | 0.77 | AR (0.48) | RORCLMNAPOLBSYKAR | |
| SCHEMBL909598 | 0.77 | AR (0.48) | RORCLMNAPOLBARNAMPT | |
| SCHEMBL21494643 | 0.76 | AR (0.48) | RORCLMNAPOLBSYKAR | |
| SCHEMBL14959644 | 0.74 | AR (0.69) | AR | |
| SCHEMBL23147917 | 0.74 | AR (0.43) | RORCSYKARRXFP1NAMPT | |
| SCHEMBL846497 | 0.73 | CNR2 (0.47) | RORCPOLBSYKTRPV1HDAC4 | |
| SCHEMBL5865312 | 0.73 | HSP90AA1 (0.53) | LMNATRPV1NAMPT | |
| SCHEMBL4166321 | 0.73 | EGFR (0.49) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104163798-A | Synthesis method of 3-amino-8-trifluoromethyl quinoline | SUZHOU KANGRUN PHARMACEUTICALS INC | 2014-11-26 | — | — | CN | disclosed |