Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RUNX1 | Q01196 | 5/20 | 0.52 |
| ▸ | ATP4A | P20648 | 7/20 | 0.41 |
| ▸ | ATP4B | P51164 | 7/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | CBFB | Q13951 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.37 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20514338 | 0.88 | ATP4A (0.49) | RUNX1ATP4AATP4BALDH1A1CYP2C9 | |
| SCHEMBL27990092 | 0.80 | RUNX1 (0.43) | RUNX1ATP4AATP4BCBFBABCB1 | |
| SCHEMBL17525958 | 0.77 | RUNX1 (0.84) | RUNX1ATP4AATP4BIGF1RCBFB | |
| SCHEMBL23988282 | 0.74 | RUNX1 (0.52) | RUNX1ATP4AATP4BALDH1A1CYP2C9 | |
| SCHEMBL23988474 | 0.73 | RUNX1 (0.51) | RUNX1ATP4AATP4BALDH1A1CYP2C9 | |
| SCHEMBL23988362 | 0.73 | RUNX1 (0.51) | RUNX1ATP4AATP4BIGF1RCBFB | |
| SCHEMBL6871855 | 0.72 | RUNX1 (0.52) | RUNX1ATP4AATP4BALDH1A1CYP2C9 | |
| SCHEMBL23988286 | 0.71 | RUNX1 (0.51) | RUNX1ATP4AATP4BIGF1RCBFB | |
| SCHEMBL6881053 | 0.71 | RUNX1 (0.51) | RUNX1ATP4AATP4BIGF1RCBFB | |
| SCHEMBL23988295 | 0.71 | RUNX1 (0.51) | RUNX1ATP4AATP4BIGF1RCBFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104114169-A | Combination of CRTH2 antagonist and a proton pump inhibitor for the treatment of eosinophilic esophagitis | ATOPIX THERAPEUTICS LTD | 2014-10-22 | — | — | CN | disclosed |