Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oleamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 4/20 | 0.64 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleamide SCHEMBL28815282 | 1.00 | FAAH (0.64) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL28407228 | 0.93 | FAAH (0.74) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Octadecanoic Acid Amide SCHEMBL27614623 | 0.91 | SOAT1 (0.47) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL28815283 | 0.89 | FAAH (0.68) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL27552866 | 0.83 | FAAH (0.85) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Oleamide SCHEMBL3177810 | 0.83 | FAAH (0.85) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| Octadecanoic Acid Amide SCHEMBL27564226 | 0.83 | SOAT1 (0.55) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL27991101 | 0.83 | EPHX2 (0.54) | FAAHCYP1A2CYP2C19KMT2AMEN1 | |
| Oleamide SCHEMBL9003110 | 0.82 | FAAH (0.77) | FAAHSOAT1CYP1A2CYP2C19KMT2A | |
| SCHEMBL9435690 | 0.82 | PPARA (0.54) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104188833-A | AQUEOUS COMPOSITION SUITABLE AS SHAMPOO | RHODIA OPERATIONS | 2014-12-10 | — | — | CN | disclosed |