Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 13/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 9/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16000745 | 0.74 | ESR2 (0.54) | ESR2KMT2AESR1KDM1ACYP3A4 | |
| SCHEMBL11865942 | 0.74 | ESR2 (0.52) | ESR2KMT2AESR1KDM1ACYP3A4 | |
| SCHEMBL6250772 | 0.73 | KDM1A (0.47) | ESR2KMT2AESR1KDM1AALDH5A1 | |
| SCHEMBL19753720 | 0.73 | ESR2 (0.48) | ESR2ESR1KDM1ACYP3A4CYP2C9 | |
| SCHEMBL1983886 | 0.70 | KDM1A (0.50) | ESR2KMT2AESR1KDM1ACYP3A4 | |
| SCHEMBL9861182 | 0.70 | ESR2 (0.48) | ESR2KMT2AESR1KDM1ACYP3A4 | |
| SCHEMBL12212987 | 0.69 | TRIM24 (0.36) | KMT2AALDH5A1ABAT | |
| SCHEMBL7975876 | 0.69 | KDM1A (0.42) | KDM1A | |
| SCHEMBL11860489 | 0.68 | KMT2A (0.48) | ESR2KMT2AESR1KDM1ACYP3A4 | |
| SCHEMBL12208421 | 0.68 | MEN1 (0.42) | KMT2AKDM1ACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104203889-A | Novel bis(4-hydroxyphenyl) cyclohexene | HONSHU CHEMICAL IND | 2014-12-10 | — | — | CN | disclosed |