Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demannose SCHEMBL3904983 | 1.00 | LMNA (0.55) | LMNAL3MBTL1TDP1PDE4AAKR1B1 | |
| Demannose SCHEMBL6750831 | 1.00 | LMNA (0.55) | LMNAL3MBTL1TDP1PDE4AAKR1B1 | |
| Galactose SCHEMBL14856251 | 1.00 | LMNA (0.55) | LMNAL3MBTL1TDP1PDE4AAKR1B1 | |
| Demannose SCHEMBL8528284 | 1.00 | LMNA (0.55) | LMNAL3MBTL1TDP1PDE4AAKR1B1 | |
| Galactose SCHEMBL1548813 | 1.00 | LMNA (0.55) | LMNAL3MBTL1TDP1PDE4AAKR1B1 | |
| Demannose SCHEMBL22712624 | 1.00 | LMNA (0.55) | LMNAL3MBTL1TDP1PDE4AAKR1B1 | |
| Demannose SCHEMBL6055085 | 1.00 | LMNA (0.55) | LMNAL3MBTL1TDP1PDE4AAKR1B1 | |
| Demannose SCHEMBL461962 | 1.00 | LMNA (0.55) | LMNAL3MBTL1TDP1PDE4AAKR1B1 | |
| Demannose SCHEMBL20817166 | 1.00 | LMNA (0.55) | LMNAL3MBTL1TDP1PDE4AAKR1B1 | |
| Demannose SCHEMBL1858493 | 1.00 | LMNA (0.55) | LMNAL3MBTL1TDP1PDE4AAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025566-A1 | IMPROVED RECOMBINANT FACTOR VII | GLYCOTOPE GMBH (DE) | 2017-02-16 | — | — | WO | claimed |
| US-10844110-B2 | O-linked glycoforms of polypeptides and method to manufacture them | NOVO NORDISK HEALTHCARE AG (CH) | 2020-11-24 | — | — | US | disclosed |
| EP-1745141-B2 | O-LINKED GLYCOFORMS OF FAKTOR VII AND METHOD TO MANUFACTURE THEM | NOVO NORDISK HEALTHCARE AG (CH) | 2019-09-25 | — | — | EP | disclosed |
| US-20180057566-A1 | O-Linked Glycoforms Of Polypeptides And Method To Manufacture Them | NOVO NORDISK HEALTHCARE AG (CH) | 2018-03-01 | — | — | US | disclosed |
| WO-2017025566-A1 | IMPROVED RECOMBINANT FACTOR VII | GLYCOTOPE GMBH (DE) | 2017-02-16 | — | — | WO | disclosed |
| US-9023992-B2 | Hydrophobic interaction chromatography purification of factor VII polypeptides | NOVO NORDISK HEALTHCARE AG (CH) | 2015-05-05 | — | — | US | disclosed |
| US-20110064719-A1 | HYDROPHOBIC INTERACTION CHROMATOGRAPHY PURIFICATION OF FACTOR VII POLYPEPTIDES | NOVO NORDISK A/S (DK) | 2011-03-17 | — | — | US | disclosed |
| EP-1745141-B1 | O-LINKED GLYCOFORMS OF FAKTOR VII AND METHOD TO MANUFACTURE THEM | NOVO NORDISK HEALTHCARE AG (CH) | 2010-01-20 | — | — | EP | disclosed |
| US-20080305518-A1 | O-Linked Glycoforms Of Polypeptides And Method To Manufacture Them | NOVO NORDISK HEALTHCARE A/G (CH) | 2008-12-11 | — | — | US | disclosed |
| EP-1952822-A1 | Factor VII polypeptides with increased affinity to platelets | NOVO NORDISK A/S (DK) | 2008-08-06 | — | — | EP | disclosed |
| WO-2008090215-A1 | FACTOR VII POLYPEPTIDES WITH INCREASED AFFINITY TO PLATELETS | NOVO NORDISK HEALTH CARE AG (DK) | 2008-07-31 | — | — | WO | disclosed |
| US-20070037966-A1 | Hydrophobic interaction chromatography purification of factor VII polypeptides | NOVO NORDISK A/S (DK) | 2007-02-15 | — | — | US | disclosed |
| EP-1745141-A1 | O-LINKED GLYCOFORMS OF POLYPEPTIDES AND METHOD TO MANUFACTURE THEM | Novo Nordisk Health Care AG (CH) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005111225-A1 | O-LINKED GLYCOFORMS OF POLYPEPTIDES AND METHOD TO MANUFACTURE THEM | NOVO NORDISK HEALTH CARE AG (CH) | 2005-11-24 | — | — | WO | disclosed |