SCHEMBL27992111

SCHEMBL27992111

CCc1cc(CN)cc(CC)c1-c1c(SC)c(C(F)(F)F)nn(C)c1=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL469890 0.91 NPC1 (0.31) POLB
SCHEMBL469877 0.86 ALDH1A1 (0.31) POLB
SCHEMBL27925983 0.84 ALDH1A1 (0.32) POLB
SCHEMBL27992390 0.84 CDK8 (0.33) POLB
SCHEMBL27992125 0.81
SCHEMBL10288372 0.75 NPC1 (0.34) POLB
SCHEMBL15063780 0.71
SCHEMBL27907825 0.71 CDK8 (0.34) POLB
SCHEMBL470030 0.70 CDK8 (0.33) POLB
SCHEMBL469898 0.70 ALDH1A1 (0.33) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104277004-B Prepare method and its intermediate of pyridazinone compound 住友化学株式会社 2016-08-24 CN disclosed
CN-104326952-B Prepare method and its intermediate of pyridazinone compound 住友化学株式会社 2016-08-24 CN disclosed
CN-103180300-B Process for producing pyridazinone compound and intermediate thereof SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-10-07 CN disclosed
CN-104326952-A METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF SUMITOMO CHEMICAL CO 2015-02-04 CN disclosed
CN-104277004-A METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF SUMITOMO CHEMICAL CO 2015-01-14 CN disclosed