Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926083 | 0.87 | GAA (0.40) | MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL28815743 | 0.86 | MEN1 (0.38) | MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL457041 | 0.84 | SMN1; SMN2 (0.36) | MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL457040 | 0.84 | SMN1; SMN2 (0.36) | MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL28079730 | 0.81 | MEN1 (0.36) | MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL27907991 | 0.81 | KMT2A (0.52) | MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL27908042 | 0.77 | BACE1 (0.34) | MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL28089974 | 0.75 | BACE1 (0.33) | MEN1GAAKMT2A | |
| SCHEMBL27908022 | 0.74 | MEN1 (0.31) | MEN1GAAKMT2A | |
| SCHEMBL27992119 | 0.74 | MAPT (0.32) | MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104326952-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-103180300-B | Process for producing pyridazinone compound and intermediate thereof | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-10-07 | — | — | CN | disclosed |
| CN-104326952-A | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL CO | 2015-02-04 | — | — | CN | disclosed |
| CN-104277004-A | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL CO | 2015-01-14 | — | — | CN | disclosed |
| CN-103180300-A | Process for producing pyridazinone compound and intermediate thereof | SUMITOMO CHEMICAL CO | 2013-06-26 | — | — | CN | disclosed |