Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908042 | 0.83 | BACE1 (0.34) | BACE1MEN1GAAKMT2ALOXL2 | |
| SCHEMBL28079730 | 0.78 | MEN1 (0.36) | BACE1MEN1GAAKMT2A | |
| SCHEMBL27926107 | 0.78 | BACE1 (0.37) | BACE1MEN1GAAKMT2ALOXL2 | |
| SCHEMBL27925977 | 0.76 | BACE1 (0.36) | BACE1MEN1GAAKMT2ALOXL2 | |
| SCHEMBL27926083 | 0.76 | GAA (0.40) | MEN1GAAKMT2A | |
| SCHEMBL27926223 | 0.75 | HTT (0.35) | BACE1MEN1GAAKMT2A | |
| SCHEMBL27992124 | 0.75 | MEN1 (0.40) | MEN1GAAKMT2A | |
| SCHEMBL27926018 | 0.72 | BACE1 (0.33) | BACE1 | |
| SCHEMBL27992341 | 0.69 | BACE1 (0.36) | BACE1MEN1GAAKMT2ALOXL2 | |
| SCHEMBL458213 | 0.66 | KDM4E (0.38) | MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104277004-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |