Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511946 | 0.80 | MAOB (0.71) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL3281151 | 0.78 | MAOB (0.53) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL30824566 | 0.78 | CA2 (0.54) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL6041859 | 0.78 | MAOB (0.53) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL6795368 | 0.78 | CA2 (0.54) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL6511944 | 0.78 | MAOB (0.63) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL2092249 | 0.78 | MAOB (0.53) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL15075824 | 0.78 | MAOB (0.53) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL1252407 | 0.78 | CA2 (0.59) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL30968743 | 0.78 | MAOB (0.49) | MAOBCA2CYP11B1CYP11B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397377-B | The method of fluorine on a kind of electron rich five-ring heterocycles acid and its derivative decarboxylation | 中南大学 | 2019-04-05 | — | — | CN | disclosed |
| CN-107735401-A | Substituted Dihydropyrrolopyrazole Derivatives | 宇部兴产株式会社 | 2018-02-23 | — | — | CN | disclosed |
| CN-104961732-A | Pyrazole Compounds as CRTH2 Antagonists | BOEHRINGER INGELHEIM INT | 2015-10-07 | — | — | CN | disclosed |
| CN-103339125-B | Pyrazole compounds as CRTH2 antagonists | BOEHRINGER INGELHEIM INT | 2015-07-15 | — | — | CN | disclosed |
| CN-104628705-A | Pyrazole compounds as CRTH2 antagonists | BOEHRINGER INGELHEIM INT | 2015-05-20 | — | — | CN | disclosed |
| CN-102459166-B | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2015-03-25 | — | — | CN | disclosed |