Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079536 | 0.86 | KMT2A (0.54) | TDP1MEN1KMT2APDE10ADHODH | |
| SCHEMBL8802391 | 0.83 | MAPT (0.51) | PIM1PIM2TDP1MEN1KMT2A | |
| SCHEMBL27884276 | 0.81 | PIM1 (0.53) | PIM1PIM2TDP1MEN1KMT2A | |
| SCHEMBL15228743 | 0.80 | PIM1 (0.44) | PIM1PIM2TDP1MEN1KMT2A | |
| SCHEMBL14734397 | 0.80 | MAPT (0.44) | MEN1KMT2APDE10ACYP1A2GPR3 | |
| SCHEMBL923856 | 0.78 | TDP1 (0.67) | TDP1MEN1KMT2APDE10ACYP1A2 | |
| SCHEMBL31135158 | 0.78 | TDP1 (0.67) | TDP1MEN1KMT2APDE10ACYP1A2 | |
| SCHEMBL30118358 | 0.77 | PIM1 (0.42) | PIM1PIM2MEN1KMT2APDE10A | |
| SCHEMBL18805356 | 0.76 | TDP1 (0.47) | TDP1MEN1KMT2APDE10ACYP1A2 | |
| SCHEMBL19169623 | 0.74 | TDP1 (0.68) | TDP1MEN1KMT2APDE10ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104262268-B | A kind of synthetic method of 2-itrile group quinoxaline compound | JIANG University OF TECHNOLOGY (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-104262268-A | Synthetic method for 2-cyano quinoxaline compound | UNIV ZHEJIANG TECHNOLOGY | 2015-01-07 | — | — | CN | disclosed |