Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | ESR1 | P03372 | 4/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397614 | 0.91 | TDP1 (0.73) | TDP1ESR1ESR2LMNANPC1 | |
| SCHEMBL16217656 | 0.86 | TDP1 (0.79) | TDP1ESR1ESR2LMNANPC1 | |
| SCHEMBL547137 | 0.86 | TDP1 (0.79) | TDP1ESR1ESR2LMNANPC1 | |
| SCHEMBL13292516 | 0.86 | TDP1 (0.79) | TDP1ESR1ESR2LMNANPC1 | |
| SCHEMBL22418 | 0.86 | TDP1 (0.59) | TDP1ESR1ESR2LMNANPC1 | |
| SCHEMBL31298566 | 0.86 | TDP1 (0.59) | TDP1ESR1ESR2LMNANPC1 | |
| SCHEMBL137486 | 0.83 | TDP1 (0.83) | TDP1ESR1ESR2LMNANPC1 | |
| SCHEMBL27782523 | 0.83 | TDP1 (0.81) | TDP1ESR1ESR2LMNANPC1 | |
| SCHEMBL19235060 | 0.81 | TDP1 (0.54) | TDP1ESR1ESR2LMNANPC1 | |
| SCHEMBL13292517 | 0.81 | TDP1 (0.54) | TDP1ESR1ESR2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104380179-A | Ophthalmic lens supply system and related methods | ESSILOR INTERNAT CIE GERERALE G OPTIQUE | 2015-02-25 | — | — | CN | disclosed |
| CN-104380180-A | Ophthalmic lenses taking into account the wearer's handedness | ESSILOR INT | 2015-02-25 | — | — | CN | disclosed |