Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | JAK1 | P23458 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27339399 | 0.88 | SMN1; SMN2 (0.85) | SMN1; SMN2GAAPKMACHEBACE1 | |
| SCHEMBL14503304 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2GAAPKMACHEBACE1 | |
| SCHEMBL5111603 | 0.80 | ALDH1A1 (0.51) | SMN1; SMN2GAAKDM4EALDH1A1KMT2A | |
| SCHEMBL8132848 | 0.78 | SMN1; SMN2 (0.74) | SMN1; SMN2GAAPKMACHEBACE1 | |
| SCHEMBL29361009 | 0.78 | SMN1; SMN2 (0.74) | SMN1; SMN2GAAPKMACHEBACE1 | |
| SCHEMBL13868011 | 0.77 | HCRTR1 (0.53) | SMN1; SMN2PKMACHEBACE1KDM4E | |
| SCHEMBL6028756 | 0.76 | MEN1 (0.55) | SMN1; SMN2GAAALDH1A1TSHRKMT2A | |
| SCHEMBL6028723 | 0.75 | MEN1 (0.55) | GAAPKMKDM4EALDH1A1TSHR | |
| SCHEMBL25344739 | 0.74 | GSK3B (0.56) | SMN1; SMN2ALDH1A1TSHRJAK1KMT2A | |
| SCHEMBL29721597 | 0.74 | GAA (0.60) | SMN1; SMN2GAAPKMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094029-A2 | ASYMMETRIC CYCLOPROPANATION WITH SUCCINIMIDYL DIAZOACETATE | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-08-19 | — | — | WO | disclosed |