SCHEMBL27994686

SCHEMBL27994686

NCc1ccc(-c2csc(=O)[nH]2)cc1

nearest known ligand 0.66

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 10/20 0.66
ALDH1A1 P00352 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.59
HRH3 Q9Y5N1 1/20 0.45
ASIC3 Q9UHC3 1/20 0.42
LTA4H P09960 1/20 0.42
NEK1 Q96PY6 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9519379 0.79 ALDH1A1 (0.62) BRD4ALDH1A1SMN1; SMN2
Bromide SCHEMBL9518983 0.78 ALDH1A1 (0.60) BRD4ALDH1A1SMN1; SMN2
SCHEMBL16415205 0.76 SMN1; SMN2 (0.92) BRD4ALDH1A1SMN1; SMN2
SCHEMBL15351910 0.76 BRD4 (0.67) BRD4ALDH1A1SMN1; SMN2GAA
SCHEMBL15351982 0.76 BRD4 (0.67) BRD4ALDH1A1SMN1; SMN2GAA
SCHEMBL16414580 0.76 BRD4 (0.67) BRD4ALDH1A1SMN1; SMN2GAA
SCHEMBL957329 0.75 SMN1; SMN2 (1.00) BRD4ALDH1A1SMN1; SMN2GAA
SCHEMBL17797070 0.73 SMN1; SMN2 (0.68) BRD4ALDH1A1SMN1; SMN2
SCHEMBL16414469 0.71 BRD4 (0.61) BRD4ALDH1A1SMN1; SMN2GAA
SCHEMBL2491364 0.71 BRD4 (0.61) BRD4ALDH1A1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104271571-B Tetrazolinone compound and use thereof 住友化学株式会社 2017-07-07 CN disclosed
CN-104271571-A Tetrazolinone compound and use thereof SUMITOMO CHEMICAL CO 2015-01-07 CN disclosed