O-Xylene

O-Xylene

SCHEMBL27995658

CNC(=N)N.Cc1ccccc1C

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ACHE P22303 1/20 0.50
PRSS1 P07477 2/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
ALDH1A1 P00352 4/20 0.41
POLB P06746 2/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39
F12 P00748 1/20 0.39
F7 P08709 1/20 0.39
F3 P13726 1/20 0.39
PKM P14618 1/20 0.39
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GRIN2D O15399 3/20 0.37
GRIN3B O60391 3/20 0.37
GRIN1 Q05586 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL27502292 0.84 ACHE (0.62) TSHRACHEPRSS1PRSS2PRSS3
Iodobenzene SCHEMBL27656481 0.81 F2 (0.41) TSHRPRSS1PRSS2PRSS3ALDH1A1
O-Xylene SCHEMBL28577267 0.80 POLB (0.52) TSHRACHEALDH1A1POLBGAA
Benzene SCHEMBL28116740 0.78 F2 (0.36) PRSS1PRSS2PRSS3ALDH1A1F2
O-Xylene SCHEMBL29074374 0.78 TSHR (0.42) TSHRACHEPRSS1PRSS2PRSS3
SCHEMBL467514 0.75 NPC1 (0.57) TSHRALDH1A1POLBGAAMAPT
O-Xylene SCHEMBL27950230 0.74 TSHR (0.77) TSHRACHEALDH1A1MAPTCYP3A4
SCHEMBL181641 0.74
Hydrochloric Acid SCHEMBL11234820 0.73 NPC1 (0.55) TSHRALDH1A1POLBGAAMAPT
Hydrochloric Acid SCHEMBL31307094 0.73 NPC1 (0.55) TSHRALDH1A1POLBGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111974166-A Regenerable solvent mixtures for acid gas separation 三角形研究学会 2020-11-24 CN disclosed
CN-104271219-B Regenerable solvent mixtures for acid gas separation 三角形研究学会 2020-08-21 CN disclosed
CN-104271219-A Regenerable solvent mixtures for acid gas separation RES TRIANGLE INST 2015-01-07 CN disclosed