Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23266636 | 0.89 | HTT (0.60) | HTTPOLBFGFR1ALDH1A1 | |
| Phenylboronic Acid SCHEMBL18192028 | 0.89 | HCAR1 (0.47) | HTTHCAR1KDM4EHPGDPOLB | |
| SCHEMBL26085163 | 0.87 | HTT (0.51) | HTTHCAR1KDM4EHPGDPOLB | |
| SCHEMBL366895 | 0.87 | HTT (0.47) | HTTHCAR1KDM4EHPGDPOLB | |
| SCHEMBL24179389 | 0.86 | HTT (0.50) | HTTHCAR1KDM4EHPGDPOLB | |
| SCHEMBL23266691 | 0.85 | HTT (0.53) | HTTHCAR1KDM4EPOLBFGFR1 | |
| SCHEMBL23266570 | 0.85 | FGFR1 (0.58) | HTTHCAR1FGFR1NPSR1MAPT | |
| SCHEMBL5791820 | 0.85 | CYP17A1 (0.50) | HTTHCAR1POLBFGFR1NPSR1 | |
| SCHEMBL23266569 | 0.84 | HTT (0.56) | HTTPOLBFGFR1 | |
| SCHEMBL3417306 | 0.83 | HTT (0.73) | HTTPOLBFGFR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105906546-A | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | 默克专利有限公司 | 2016-08-31 | — | — | CN | claimed |
| CN-102317408-B | Organic electronic device | MERCK PATENT GMBH | 2015-03-04 | — | — | CN | claimed |
| CN-104327003-A | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH | 2015-02-04 | — | — | CN | claimed |
| CN-103539818-B | Bipolarity phosphorescence host compound, preparation method and application and electroluminescent device | TCL集团股份有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105906546-A | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | 默克专利有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-102317408-B | Organic electronic device | MERCK PATENT GMBH | 2015-03-04 | — | — | CN | disclosed |
| CN-104327003-A | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH | 2015-02-04 | — | — | CN | disclosed |