Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27286637 | 1.00 | ELANE (0.41) | ELANEPTPN1KCNN4CYP2C19HIF1A | |
| SCHEMBL435821 | 0.93 | ELANE (0.45) | ELANEKCNN4CYP2C19HIF1ACYP1A2 | |
| SCHEMBL27859061 | 0.92 | ELANE (0.43) | ELANEPTPN1KCNN4CYP2C19HIF1A | |
| Phosphine SCHEMBL27261108 | 0.91 | ELANE (0.44) | ELANEKCNN4CYP2C19HIF1ACYP1A2 | |
| Acetic Acid SCHEMBL28277118 | 0.91 | ELANE (0.44) | ELANEKCNN4CYP2C19HIF1ACYP1A2 | |
| Bicarbonate SCHEMBL27420408 | 0.91 | ELANE (0.44) | ELANEKCNN4CYP2C19HIF1ACYP1A2 | |
| Triphenyl Phosphate SCHEMBL28314264 | 0.90 | SRC (0.40) | ELANEPTPN1ALDH1A1TDP1SRC | |
| SCHEMBL28845220 | 0.90 | ELANE (0.42) | ELANEKCNN4CYP2C19HIF1ACYP1A2 | |
| Methacrylic Acid SCHEMBL27752618 | 0.90 | ELANE (0.42) | ELANEKCNN4CYP2C19HIF1ACYP1A2 | |
| Triphosphate SCHEMBL27996368 | 0.90 | ELANE (0.36) | ELANEPTPN1KCNN4CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503931-A | Wear-resisting anti-oxidant PE films of one kind and preparation method thereof | 班戈设备系统（苏州）有限公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-108503931-A | Wear-resisting anti-oxidant PE films of one kind and preparation method thereof | 班戈设备系统（苏州）有限公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-104327348-A | Flame-retardant polyethylene-polypropylene composite plastic | QINGDAO DTCN NEW MATERIAL TECHNOLOGY DEV CO LTD | 2015-02-04 | — | — | CN | disclosed |