Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15800205 | 0.87 | KDM4E (0.67) | KDM4EALDH1A1CHRM2ACHENPC1 | |
| SCHEMBL28577080 | 0.87 | KDM4E (0.60) | KDM4EALDH1A1CHRM2ACHENPC1 | |
| SCHEMBL28572335 | 0.87 | KDM4E (0.60) | KDM4EALDH1A1CHRM2ACHENPC1 | |
| SCHEMBL28914380 | 0.86 | KDM4E (0.59) | KDM4EALDH1A1CHRM2ACHENPC1 | |
| SCHEMBL28896706 | 0.82 | CHRM2 (0.60) | KDM4EALDH1A1CHRM2ACHENPC1 | |
| SCHEMBL24274178 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1NPC1RAB9AHRH3 | |
| SCHEMBL25634668 | 0.78 | CHRM2 (0.62) | KDM4EALDH1A1CHRM2ACHENPC1 | |
| SCHEMBL14174789 | 0.77 | ALDH1A1 (0.67) | KDM4EALDH1A1NPC1RAB9AHRH3 | |
| SCHEMBL24274180 | 0.77 | KDM4E (0.71) | KDM4EALDH1A1NPC1RAB9AHRH3 | |
| SCHEMBL30540074 | 0.77 | KDM4E (0.60) | KDM4EALDH1A1NPC1RAB9AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958916-B | Process for preparing a biphenyl-2-ylcarbamic acid | THERAVANCE BIOPHARMA R & D IP LLC | 2015-03-25 | — | — | CN | disclosed |