Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESD | P10768 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 11/20 | 0.52 |
| ▸ | MAOA | P21397 | 5/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292699 | 0.86 | ESD (0.75) | ESDMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL27997620 | 0.79 | ESD (0.65) | ESDMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL6294300 | 0.77 | ESD (0.63) | ESDMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL6298090 | 0.77 | ESD (0.61) | ESDMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL27997398 | 0.76 | ESD (0.61) | ESDMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL6298325 | 0.75 | ESD (0.60) | ESDMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL6298319 | 0.75 | PDE5A (0.65) | ESDMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL6294160 | 0.74 | ESD (0.58) | ESDMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL4942223 | 0.71 | ESD (0.55) | ESDMEN1KMT2AATMPRKCZ | |
| SCHEMBL22795865 | 0.71 | ESD (0.55) | ESDMEN1KMT2AATMPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104288149-B | Application of 4-chloro-2-(5-phenyl-1-(pyridine-2-yl)-4, 5-dihydro-1H-pyrazol-3-yl) phenol in pharmacy | 山东大学 | 2017-02-15 | — | — | CN | disclosed |
| CN-104288149-B | Application of 4-chloro-2-(5-phenyl-1-(pyridine-2-yl)-4, 5-dihydro-1H-pyrazol-3-yl) phenol in pharmacy | 山东大学 | 2017-02-15 | — | — | CN | disclosed |
| CN-104288149-A | Application of 4-chloro-2-(5-phenyl-1-(pyridine-2-yl)-4, 5-dihydro-1H-pyrazol-3-yl) phenol in pharmacy | UNIV SHANDONG | 2015-01-21 | — | — | CN | disclosed |
| CN-104288149-A | Application of 4-chloro-2-(5-phenyl-1-(pyridine-2-yl)-4, 5-dihydro-1H-pyrazol-3-yl) phenol in pharmacy | UNIV SHANDONG | 2015-01-21 | — | — | CN | disclosed |
| CN-104288149-A | Application of 4-chloro-2-(5-phenyl-1-(pyridine-2-yl)-4, 5-dihydro-1H-pyrazol-3-yl) phenol in pharmacy | UNIV SHANDONG | 2015-01-21 | — | — | CN | disclosed |