Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359896 | 1.00 | NR3C2 (0.57) | NR3C2ALDH1A1MAPTHTTKDM4E | |
| SCHEMBL2357968 | 0.93 | NR3C2 (0.57) | NR3C2ALDH1A1MAPTHTTKDM4E | |
| SCHEMBL2357327 | 0.91 | NR3C2 (0.60) | NR3C2ALDH1A1MAPTHTTKDM4E | |
| SCHEMBL2358996 | 0.89 | NR3C2 (0.62) | NR3C2ALDH1A1MAPTHTTKDM4E | |
| SCHEMBL2357188 | 0.89 | NR3C2 (0.71) | NR3C2MAPTELANE | |
| SCHEMBL27997697 | 0.89 | NR3C2 (0.71) | NR3C2MAPTELANE | |
| SCHEMBL27997474 | 0.88 | NR3C2 (0.66) | NR3C2ALDH1A1MAPTHTTKDM4E | |
| SCHEMBL2358756 | 0.88 | NR3C2 (0.66) | NR3C2ALDH1A1MAPTHTTKDM4E | |
| SCHEMBL2357294 | 0.88 | NR3C2 (0.67) | NR3C2ALDH1A1MAPTHTTKDM4E | |
| SCHEMBL16456899 | 0.86 | NR3C2 (0.46) | NR3C2ALDH1A1MAPTHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102177137-B | 1-phenylpyrrole compounds | EXELIXIS INC | 2015-03-18 | — | — | CN | disclosed |