Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.37 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357188 | 1.00 | NR3C2 (0.71) | NR3C2PTGS2AVPR2GPR27ELANE | |
| SCHEMBL2357023 | 0.90 | NR3C2 (0.77) | NR3C2AVPR2GPR27MAPTGAA | |
| SCHEMBL2358752 | 0.90 | NR3C2 (0.74) | NR3C2PTGS2AVPR2GPR27 | |
| SCHEMBL2359896 | 0.89 | NR3C2 (0.57) | NR3C2ELANEMAPT | |
| SCHEMBL2357968 | 0.89 | NR3C2 (0.57) | NR3C2ELANEMAPT | |
| SCHEMBL27997693 | 0.89 | NR3C2 (0.57) | NR3C2ELANEMAPT | |
| SCHEMBL2359373 | 0.89 | NR3C2 (0.77) | NR3C2PTGS2AVPR2GPR27MAPT | |
| SCHEMBL2359163 | 0.87 | NR3C2 (0.81) | NR3C2PTGS2AVPR2GPR27 | |
| SCHEMBL27997692 | 0.87 | NR3C2 (0.81) | NR3C2PTGS2AVPR2GPR27 | |
| SCHEMBL2359060 | 0.87 | NR3C2 (0.83) | NR3C2PTGS2AVPR2GPR27ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102177137-B | 1-phenylpyrrole compounds | EXELIXIS INC | 2015-03-18 | — | — | CN | disclosed |