Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27998087 | 0.91 | MAPT (0.42) | MAPTTP53GAAPDE4DCYP3A4 | |
| SCHEMBL19210511 | 0.87 | MAPT (0.36) | MAPTTP53CYP3A4CYP2C9PDE11A | |
| SCHEMBL27997990 | 0.80 | MEN1 (0.31) | SMN1; SMN2KMT2A | |
| SCHEMBL16344814 | 0.79 | PDE4D (0.53) | MAPTTP53GAAPDE4DCYP3A4 | |
| SCHEMBL27997746 | 0.78 | MAPT (0.32) | MAPTPOLBSMN1; SMN2 | |
| SCHEMBL19210485 | 0.77 | MAPT (0.44) | MAPTGAACYP3A4CYP2C9PDE11A | |
| SCHEMBL16344301 | 0.76 | POLB (0.42) | MAPTGAACYP2C9HPGDPOLB | |
| SCHEMBL19210509 | 0.75 | MAPT (0.36) | MAPTTP53GAAPDE4DCYP3A4 | |
| SCHEMBL27997974 | 0.72 | CYP1A2 (0.32) | CYP3A4CYP2C9SMN1; SMN2KMT2ACYP2C19 | |
| SCHEMBL16344779 | 0.71 | PDE4D (0.55) | MAPTTP53GAAPDE4DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245676-B | Process for producing 3, 5-bis (fluoroalkyl) pyrazole-4-carboxylic acid derivative and 3, 5-bis (fluoroalkyl) pyrazole compound | 拜耳农作物科学股份公司 | 2016-09-21 | — | — | CN | disclosed |
| CN-104245676-A | Process for producing 3, 5-bis (fluoroalkyl) pyrazole-4-carboxylic acid derivative and 3, 5-bis (fluoroalkyl) pyrazole compound | BAYER CROPSCIENCE AG | 2014-12-24 | — | — | CN | disclosed |