Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210511 | 0.90 | MAPT (0.36) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL19210509 | 0.90 | MAPT (0.36) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL27998087 | 0.87 | MAPT (0.42) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL27997750 | 0.82 | MAPT (0.38) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL16344251 | 0.80 | POLB (0.50) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL27997992 | 0.77 | MAPT (0.40) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL15158195 | 0.76 | PKM (0.32) | NPC1 | |
| SCHEMBL16344779 | 0.75 | PDE4D (0.55) | MAPTALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL19210481 | 0.74 | ATM (0.30) | — | |
| SCHEMBL16344203 | 0.72 | POLB (0.42) | MAPTSMN1; SMN2POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2809653-B1 | METHOD FOR PRODUCING 3,5-BIS(FLUORALKYL)-PYRAZOL-4-CARBOXYLIC ACID DERIVATIVES AND 3,5-BIS(FLUORALKYL)-PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2017-08-16 | — | — | EP | disclosed |