Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30361484 | 0.91 | SMN1; SMN2 (0.63) | HPGDLMNASMN1; SMN2EGLN1MEN1 | |
| SCHEMBL26102905 | 0.91 | SMN1; SMN2 (0.63) | HPGDLMNASMN1; SMN2EGLN1MEN1 | |
| SCHEMBL18715195 | 0.86 | HPGD (0.71) | HPGDLMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL21261436 | 0.86 | HPGD (0.70) | HPGDLMNASMN1; SMN2EGLN1MEN1 | |
| SCHEMBL921981 | 0.86 | HPGD (0.70) | HPGDLMNASMN1; SMN2EGLN1MEN1 | |
| SCHEMBL8376695 | 0.85 | HPGD (0.61) | HPGDLMNASMN1; SMN2KMT2APOLB | |
| SCHEMBL12142857 | 0.85 | NSD2 (0.66) | HPGDLMNAEGLN1MEN1MAPT | |
| SCHEMBL31569526 | 0.85 | NSD2 (0.66) | HPGDLMNAEGLN1MEN1MAPT | |
| SCHEMBL13070250 | 0.83 | HPGD (0.66) | HPGDLMNASMN1; SMN2EGLN1MEN1 | |
| SCHEMBL921037 | 0.83 | HPGD (0.66) | HPGDLMNASMN1; SMN2EGLN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507941-A | Aryllactam Kinase Inhibitors | BRISTOL MYERS SQUIBB CO | 2015-04-08 | — | — | CN | disclosed |