SCHEMBL921037

SCHEMBL921037

COc1ccc(Oc2ccc(CNC(=O)c3cccnc3N)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.66
LMNA P02545 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
EGLN1 Q9GZT9 1/20 0.60
KMT2A Q03164 3/20 0.59
MEN1 O00255 2/20 0.59
MAPT P10636 2/20 0.59
ALDH1A1 P00352 2/20 0.58
POLB P06746 2/20 0.56
MAPK8 P45983 2/20 0.55
RAB9A P51151 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921981 0.96 HPGD (0.70) HPGDLMNASMN1; SMN2EGLN1KMT2A
SCHEMBL13070250 0.93 HPGD (0.66) HPGDLMNASMN1; SMN2EGLN1KMT2A
SCHEMBL921271 0.92 HPGD (0.57) HPGDLMNASMN1; SMN2EGLN1KMT2A
SCHEMBL921980 0.91 HPGD (0.64) HPGDLMNASMN1; SMN2EGLN1KMT2A
SCHEMBL922484 0.91 HPGD (0.62) HPGDLMNASMN1; SMN2EGLN1ALDH1A1
SCHEMBL920473 0.91 HPGD (0.57) HPGDLMNASMN1; SMN2EGLN1KMT2A
SCHEMBL920461 0.90 MAPK8 (0.67) HPGDLMNASMN1; SMN2KMT2AMEN1
SCHEMBL920077 0.90 HPGD (0.62) HPGDLMNASMN1; SMN2KMT2AMEN1
SCHEMBL923664 0.90 ALDH1A1 (0.69) HPGDLMNASMN1; SMN2EGLN1KMT2A
SCHEMBL920793 0.89 LMNA (0.61) HPGDLMNASMN1; SMN2EGLN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885LMNA 4812/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.