Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 18/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 15/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000333 | 0.89 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1 | |
| SCHEMBL15525676 | 0.84 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL15525675 | 0.84 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1 | |
| SCHEMBL15525931 | 0.82 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1MAOB | |
| SCHEMBL16687051 | 0.81 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1 | |
| SCHEMBL26447852 | 0.78 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1 | |
| SCHEMBL16569651 | 0.76 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1 | |
| SCHEMBL15526033 | 0.75 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1 | |
| SCHEMBL15526024 | 0.75 | MAPK1 (0.44) | HSP90AA1HSP90AB1 | |
| SCHEMBL24321693 | 0.74 | PDK1 (0.44) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470941-A | Targeted therapeutics | SYNTA PHARMACEUTICALS CORP | 2015-03-25 | — | — | CN | disclosed |