Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrahexylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL29168875 | 0.95 | PRCP (0.54) | PRCPDPP7TLR2SLC22A1S1PR3 | |
| Tetrabuthylammonium SCHEMBL23877942 | 0.95 | PRCP (0.54) | PRCPDPP7TLR2SLC22A1S1PR3 | |
| Proline SCHEMBL28032319 | 0.84 | PRCP (0.56) | PRCPDPP7TLR2S1PR3ALDH1A1 | |
| Proline SCHEMBL28101561 | 0.84 | PRCP (0.56) | PRCPDPP7TLR2S1PR3ALDH1A1 | |
| Proline SCHEMBL29262501 | 0.84 | PRCP (0.56) | PRCPDPP7TLR2S1PR3ALDH1A1 | |
| Dodecanoate SCHEMBL17223919 | 0.84 | PRCP (0.56) | PRCPTLR2ALDH1A1ALOX15TSHR | |
| Proline SCHEMBL27518126 | 0.84 | PRCP (0.56) | PRCPDPP7TLR2S1PR3ALDH1A1 | |
| Palmitamide SCHEMBL2983849 | 0.83 | PRCP (0.55) | PRCPDPP7TLR2S1PR3ALDH1A1 | |
| Proline SCHEMBL30939428 | 0.83 | PRCP (0.55) | PRCPDPP7TLR2S1PR3ALDH1A1 | |
| Proline SCHEMBL28014194 | 0.83 | PRCP (0.54) | PRCPDPP7TLR2S1PR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470633-B | CO 2 sorption by supported amino acid ionic liquids | 丹麦科技大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-104470633-A | CO Via loaded amino acid Ionic liquids2Sorption action | UNIV DENMARK TECH DTU | 2015-03-25 | — | — | CN | disclosed |