Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30513592 | 0.85 | P2RX7 (0.41) | P2RX7CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL724189 | 0.85 | P2RX7 (0.41) | P2RX7CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL18124487 | 0.83 | AR (0.40) | P2RX7CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL29656253 | 0.83 | P2RX7 (0.39) | P2RX7CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL15532671 | 0.81 | P2RX7 (0.41) | P2RX7CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL10124833 | 0.81 | P2RX7 (0.39) | P2RX7CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL4617148 | 0.81 | SMN1; SMN2 (0.48) | P2RX7CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL3126891 | 0.80 | IDO1 (0.52) | SLC6A2SLC6A4IDO1MAOB | |
| SCHEMBL30252413 | 0.80 | IDO1 (0.52) | SLC6A2SLC6A4IDO1MAOB | |
| Hydrochloric Acid SCHEMBL6965231 | 0.80 | SMN1; SMN2 (0.50) | P2RX7CYP2D6SLC6A2SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104395310-A | Bicyclic substituted uracils and their use | Bayer Pharma AG | 2015-03-04 | — | — | CN | disclosed |