SCHEMBL28000795

SCHEMBL28000795

CC(C)c1cccc(C(C)C)c1CC(N)CN

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
SLC6A2 P23975 3/20 0.40
HTR2C P28335 2/20 0.40
HTR2B P41595 2/20 0.40
GABRB2 P47870 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
LMNA P02545 2/20 0.40
FAAH O00519 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
GABRB1 P18505 1/20 0.40
PTGS1 P23219 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19290002 0.77 GABRA1 (0.47) GABRA1GABRG2GABRB3SLC6A2HTR2C
SCHEMBL3842621 0.76 GABRA1 (0.60) GABRA1GABRG2GABRB3SLC6A2HTR2C
SCHEMBL10391946 0.75 SCN4A (0.40) SLC6A2HTR2BCYP1A2CYP3A4LMNA
SCHEMBL16273856 0.74 GABRA1 (0.44) GABRA1GABRG2GABRB3SLC6A2HTR2C
SCHEMBL813655 0.74 GABRA1 (0.41) GABRA1GABRG2GABRB3SLC6A2HTR2C
SCHEMBL813212 0.74 GABRA1 (0.41) GABRA1GABRG2GABRB3SLC6A2HTR2C
SCHEMBL3844252 0.72 GABRA1 (0.56) GABRA1GABRG2GABRB3SLC6A2HTR2C
SCHEMBL19289796 0.72 GABRA1 (0.50) GABRA1GABRG2GABRB3SLC6A2HTR2C
SCHEMBL2511832 0.71 TAAR1 (0.50) SLC6A2HTR2CHTR2BCYP1A2CYP3A4
SCHEMBL1815884 0.71 GABRA1 (0.43) GABRA1GABRG2GABRB3SLC6A2HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104628730-B A kind of optical homochiral cyclic n nitroso compound, the synthetic method of N acetals 中山大学 2018-01-30 CN disclosed
CN-104628730-A Method for synthesizing optical pure chiral cyclic N,N-acetal UNIV SUN YAT SEN 2015-05-20 CN disclosed
CN-104311559-A Synthetic method of optically pure chiral annular N, N-acetal UNIV SUN YAT SEN 2015-01-28 CN disclosed