SCHEMBL28001057

SCHEMBL28001057

Cc1cc(Cl)ccc1OCC(=O)NC(F)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.57
MAPT P10636 4/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
TP53 P04637 1/20 0.56
HTT P42858 1/20 0.56
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
ANO1 Q5XXA6 4/20 0.55
ANO2 Q9NQ90 1/20 0.55
OPRM1 P35372 1/20 0.54
OPRD1 P41143 1/20 0.54
CTDSP1 Q9GZU7 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.53
LMNA P02545 2/20 0.53
HPGD P15428 1/20 0.53
SCN4A P35499 1/20 0.52
MCHR1 Q99705 1/20 0.52
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28001411 0.86 NPSR1 (0.57) NPSR1MAPTL3MBTL1TP53HTT
SCHEMBL10485687 0.85 ANO1 (0.56) NPSR1MAPTL3MBTL1TP53HTT
SCHEMBL1195259 0.80 NPSR1 (0.62) NPSR1MAPTL3MBTL1TP53HTT
SCHEMBL1195260 0.80 NPSR1 (0.62) NPSR1MAPTL3MBTL1TP53HTT
SCHEMBL10857636 0.79 NOTUM (0.70) NPSR1MAPTL3MBTL1TP53HTT
SCHEMBL1194561 0.78 MEN1 (0.57) NPSR1MAPTL3MBTL1HTTMEN1
SCHEMBL1194560 0.78 MEN1 (0.57) NPSR1MAPTL3MBTL1HTTMEN1
SCHEMBL11602472 0.76 NPSR1 (0.57) NPSR1MAPTL3MBTL1TP53HTT
SCHEMBL10610907 0.76 NPSR1 (0.67) NPSR1MAPTL3MBTL1TP53HTT
SCHEMBL9722109 0.75 ALDH1A1 (0.72) NPSR1MAPTL3MBTL1TP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103694197-B Phenoxyacetamide compound and preparation method and application thereof UNIV HUAZHONG NORMAL 2015-07-15 CN disclosed