Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548013 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1LMNAKCNH2NQO1 | |
| SCHEMBL8751807 | 0.81 | NQO1 (0.63) | KDM4EALDH1A1NQO1SMN1; SMN2 | |
| SCHEMBL15114753 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1LMNAKCNH2SMN1; SMN2 | |
| SCHEMBL27730066 | 0.79 | NQO1 (0.50) | KDM4EALDH1A1LMNAKCNH2NQO1 | |
| SCHEMBL23216195 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1LMNAKCNH2SMN1; SMN2 | |
| SCHEMBL29512405 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1LMNAKCNH2SMN1; SMN2 | |
| SCHEMBL13969487 | 0.77 | LTA4H (0.57) | KDM4EKCNH2NQO1FFAR1HSP90AA1 | |
| SCHEMBL12885024 | 0.76 | KDM4E (0.69) | KDM4EALDH1A1LMNAKCNH2SMN1; SMN2 | |
| SCHEMBL13261015 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1LMNAKCNH2SMN1; SMN2 | |
| SCHEMBL24854715 | 0.76 | KMT2A (0.51) | KDM4ELMNAKCNH2SMN1; SMN2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447792-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI AVENTIS | 2015-03-25 | — | — | CN | disclosed |