Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933210 | 0.81 | CA1 (0.46) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL14866959 | 0.81 | APP (0.42) | APPKMT2ANR4A2RXRARXRB | |
| SCHEMBL4367676 | 0.80 | APP (0.55) | APPKMT2ANR4A2RXRARXRB | |
| SCHEMBL10202405 | 0.79 | APP (0.41) | APPKMT2ANR4A2RXRARXRB | |
| SCHEMBL2405469 | 0.78 | IDO1 (0.45) | APPKMT2ARAB9ACA1CA2 | |
| SCHEMBL2405472 | 0.78 | IDO1 (0.45) | APPKMT2ARAB9ACA1CA2 | |
| SCHEMBL28775048 | 0.78 | CYP3A4 (0.45) | APPKMT2ACA1CA2CA7 | |
| SCHEMBL10973793 | 0.78 | HTT (0.57) | KMT2ARAB9ATSHRLMNACA1 | |
| SCHEMBL873616 | 0.77 | CA1 (0.61) | KMT2ATSHRLMNACA1CA2 | |
| SCHEMBL12172311 | 0.77 | HSD17B10 (0.50) | KMT2ARAB9ALMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447792-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI AVENTIS | 2015-03-25 | — | — | CN | disclosed |