Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258103 | 0.86 | LMNA (0.50) | LMNAADRB2ADRB1ADRB3HRH3 | |
| SCHEMBL16179945 | 0.81 | MAOB (0.41) | MAOBAOC3MAOACARM1PRMT6 | |
| SCHEMBL5949941 | 0.80 | LMNA (0.78) | LMNAADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL15664329 | 0.79 | KMT2A (0.56) | MAOBAOC3ADRB3KCNH2KMT2A | |
| SCHEMBL1835550 | 0.79 | LMNA (0.64) | LMNAKCNH2KMT2A | |
| SCHEMBL1840653 | 0.79 | LMNA (0.64) | LMNAKCNH2KMT2A | |
| SCHEMBL6273026 | 0.79 | LMNA (0.64) | LMNAKCNH2KMT2A | |
| SCHEMBL5962530 | 0.78 | MAOB (0.41) | MAOBAOC3MAOAADRB3 | |
| SCHEMBL1241813 | 0.76 | LMNA (0.73) | LMNAADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL11459339 | 0.76 | LMNA (0.55) | LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447792-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI AVENTIS | 2015-03-25 | — | — | CN | disclosed |