SCHEMBL2800157

SCHEMBL2800157

N[C]1CCCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3667791 1.00
SCHEMBL155648 1.00
Methane SCHEMBL15013268 0.96 NOS3 (0.38)
SCHEMBL612554 0.96 NOS3 (0.38)
SCHEMBL583260 0.95
Hydrochloric Acid SCHEMBL13386458 0.92 NOS3 (0.41)
SCHEMBL143894 0.80
SCHEMBL13348019 0.73 NOS3 (0.40)
SCHEMBL3676789 0.73 NOS3 (0.40)
SCHEMBL12514471 0.73 NOS3 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148722-A1 SMALL MOLECULES THAT BIND TO TDP-43 FOR THE TREATMENT OF ALS AND RELATED DISORDERS FOX CHASE CHEMICAL DIVERSITY CENTER INC. 2024-05-09 US claimed
EP-3250191-B1 TABLETS COMPRISING GLP-1 AGONIST AND ENTERIC COATING NOVO NORDISK AS (DK) 2024-01-17 EP claimed
EP-4294811-A2 SMALL MOLECULES THAT BIND TO TDP-43 FOR THE TREATMENT OF ALS AND RELATED DISORDERS Biohaven Therapeutics Ltd. (US) 2023-12-27 EP claimed
EP-2637698-B1 DOUBLE-ACYLATED GLP-1 DERIVATIVES NOVO NORDISK AS (DK) 2022-04-20 EP claimed
EP-2932981-B1 Albumin-binding derivatives of GLP-1 NOVO NORDISK AS (DK) 2021-06-16 EP claimed
EP-3225631-B1 DOUBLE-ACYLATED GLP-1 DERIVATIVES NOVO NORDISK AS (DK) 2019-01-09 EP claimed
US-9943512-B2 Drug treatment of overactive bladder BLEBBICORP, LLC 2018-04-17 US claimed
US-20170020861-A1 DRUG TREATMENT OF OVERACTIVE BLADDER BLEBBICORP, LLC 2017-01-26 US claimed
US-20160375003-A1 DRUG TREATMENT OF OVERACTIVE BLADDER BLEBBICORP, LLC 2016-12-29 US claimed
US-9492441-B2 Drug treatment of overactive bladder BLEBBICORP, LLC 2016-11-15 US claimed
EP-1863839-B1 ACYLATED GLP-1 COMPOUNDS NOVO NORDISK AS (DK) 2010-08-04 EP claimed
CN-1391474-A 5-membered heterocyclic derivatives, their preparation and their use as medicaments SOD CONSEILS RECH APPLIC (FR) 2003-01-15 CN claimed
US-20240148722-A1 SMALL MOLECULES THAT BIND TO TDP-43 FOR THE TREATMENT OF ALS AND RELATED DISORDERS FOX CHASE CHEMICAL DIVERSITY CENTER INC. 2024-05-09 US disclosed
WO-2024054807-A1 COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-03-14 WO disclosed
US-11884647-B2 Compounds and methods for targeting pathogenic blood vessels THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-30 US disclosed
EP-4294811-A2 SMALL MOLECULES THAT BIND TO TDP-43 FOR THE TREATMENT OF ALS AND RELATED DISORDERS Biohaven Therapeutics Ltd. (US) 2023-12-27 EP disclosed
WO-2007102059-A1 SULFONYL BENZIMIDAZOLE DERIVATIVES PFIZER JAPAN INC. (JP) 2007-09-13 WO disclosed
EP-0022997-B1 2,2,6,6-TETRAMETHYL-4-PIPERIDYL CARBOXYLIC ACID ESTERS AND AMIDES OF MONO AND POLY ALCOHOLS, PHENOLS AND AMINES AND SYNTHETIC POLYMER COMPOSITIONS STABILIZED THEREBY ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1985-10-02 EP disclosed
US-4336183-A 2,2,6,6-Tetramethyl-4-piperidyl carboxylic acid esters and amides of mono and poly alcohols, phenols and amines as stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-06-22 US disclosed
EP-0022997-A1 2,2,6,6-Tetramethyl-4-piperidyl carboxylic acid esters and amides of mono and poly alcohols, phenols and amines and synthetic polymer compositions stabilized thereby ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-01-28 EP disclosed