Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12066225 | 0.88 | PDE10A (1.00) | PDE10AMEN1MAPTKMT2A | |
| SCHEMBL230753 | 0.79 | HRH1 (0.73) | MAPTHRH1CYP1A2CYP2D6HRH3 | |
| SCHEMBL29485678 | 0.79 | HRH1 (0.73) | MAPTHRH1CYP1A2CYP2D6HRH3 | |
| SCHEMBL28237594 | 0.79 | PDE10A (0.81) | PDE10AMEN1MAPTKMT2ALMNA | |
| SCHEMBL22501412 | 0.78 | KDM4E (0.57) | PDE10AHRH1CYP1A2CYP2D6HRH3 | |
| Bromide SCHEMBL28641396 | 0.77 | HRH1 (0.70) | MAPTHRH1CYP1A2CYP2D6HRH3 | |
| SCHEMBL9971272 | 0.77 | PDE10A (0.77) | PDE10AMEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL7317271 | 0.77 | PDE10A (0.77) | PDE10AMEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL7317281 | 0.77 | PDE10A (0.77) | PDE10AMEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL8408826 | 0.77 | PDE10A (0.77) | PDE10AMEN1MAPTKMT2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529889-B | A kind of dehydration C- alkylations of heterocyclic methyl compound | 温州大学 | 2018-09-04 | — | — | CN | disclosed |
| CN-104529889-A | Dehydration C-alkylation method for heterocyclic methyl compound | UNIV WENZHOU | 2015-04-22 | — | — | CN | disclosed |