SCHEMBL230753

SCHEMBL230753

c1ccc(CCc2ccccn2)nc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.73
HRH3 Q9Y5N1 2/20 0.64
CYP1A2 P05177 3/20 0.63
CYP2D6 P10635 1/20 0.63
ALDH1A1 P00352 2/20 0.61
LMNA P02545 1/20 0.61
TAAR1 Q96RJ0 1/20 0.61
ALOX15 P16050 1/20 0.61
HRH4 Q9H3N8 1/20 0.59
MAPT P10636 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
LIN28A Q9H9Z2 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
CYP2C19 P33261 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29485678 1.00 HRH1 (0.73) HRH1HRH3CYP1A2CYP2D6ALDH1A1
Bromide SCHEMBL28641396 0.97 HRH1 (0.70) HRH1HRH3CYP1A2CYP2D6ALDH1A1
SCHEMBL10452255 0.92 HRH1 (0.64) HRH1HRH3CYP1A2CYP2D6ALDH1A1
SCHEMBL29485637 0.89 HRH1 (0.69) HRH1HRH3CYP1A2CYP2D6ALDH1A1
SCHEMBL231470 0.89 HRH1 (0.69) HRH1HRH3CYP1A2CYP2D6ALDH1A1
SCHEMBL726512 0.89 HRH1 (0.76) HRH1HRH3CYP1A2CYP2D6ALDH1A1
SCHEMBL25298622 0.88 HRH1 (0.59) HRH1HRH3CYP1A2CYP2D6ALDH1A1
SCHEMBL29572974 0.88 CYP1A2 (0.69) HRH1HRH3CYP1A2CYP2D6ALDH1A1
SCHEMBL1760766 0.88 CYP1A2 (0.69) HRH1HRH3CYP1A2CYP2D6ALDH1A1
SCHEMBL4418086 0.87 HRH1 (0.80) HRH1HRH3CYP1A2CYP2D6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 760 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410170-A Icaritin eutectic 山东新时代药业有限公司 2023-07-11 CN claimed
CN-110416546-B Preparation method and application of three-dimensional self-supporting nitrogen-doped carbon sodium ion negative electrode material 湖北大学 2021-04-30 CN claimed
CN-110416546-A The preparation method and application of three-dimensional self-supporting nitrogen-doped carbon sodium ion negative electrode material UNIV HUBEI 2019-11-05 CN claimed
CN-106459095-A Metal organic framework (MOF) yellow phosphors and their applications in white light emitting devices 新泽西鲁特格斯州立大学 2017-02-22 CN claimed
EP-1398671-B1 Resist pattern thickening material, process for forming resist pattern, and process for manufacturing semiconductor device FUJITSU LTD (JP) 2016-06-01 EP claimed
US-8182718-B2 Ligand exchange thermochromic systems and high ε ligands for same PLEOTINT, L.L.C. (US) 2012-05-22 US claimed
EP-1085012-B1 PROCESS FOR PRODUCING A PURIFIED PROSTAGLANDIN DERIVATIVE ASAHI GLASS CO LTD (JP) 2008-10-29 EP claimed
EP-0526603-B1 Use of Mono, Bis or Tris (2,2'-substituted Bipyridine) complexes of a transition metal as mediators for current sensors ASULAB SA (CH) 1996-12-04 EP claimed
WO-1995021030-A1 EFFICIENT CHEMISTRY FOR SELECTIVE MODIFICATION AND METALLIZATION OF SUBSTRATES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1995-08-10 WO claimed
US-5393903-A Mediator composition for coating an electrode of an amperometric sensor; for glucose testing in biological fluids ASULAB S.A. (CH) 1995-02-28 US claimed
EP-0338504-B1 Photosensitive member for electrophotography CANON KK (JP) 1994-08-24 EP claimed
EP-0433642-A1 Karl-Fischer reagent and process for the determination of water by using the reagent MERCK PATENT GmbH (DE) 1991-06-26 EP claimed
US-5008168-A Trimethyl trihdroxyphenyl substituted benzene, triphenyl phosp hite CANON KABUSHIKI KAISHA (JP) 1991-04-16 US claimed
EP-0338504-A2 Photosensitive member for electrophotography CANON KABUSHIKI KAISHA (JP) 1989-10-25 EP claimed
US-12624016-B2 Salt, acid generator, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-05-12 US disclosed
US-12619145-B2 Carboxylate, carboxylic acid generator, resin, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-05-05 US disclosed
US-20260118758-A1 SALT, ACID GENERATOR, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-04-30 US disclosed
US-4427828-A Impact resistant polymeric compositions containing polyamides, maleic anhydride adducts of hydrogenated polymers and graft copolymers thereof THE FIRESTONE TIRE & RUBBER COMPANY (US) 1984-01-24 US disclosed
US-4248632-A ACTIVATION OF A POLYMER SURFACE WITH A PALLADIUM COMPLEX SALT SCHERING AKTIENGESELLSCHAFT (DE) 1981-02-03 US disclosed
US-4006149-A COBALT CONTAINING STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12619145-B2 Carboxylate, carboxylic acid generator, resin, resist composition and method for producing resist pattern MSR1, H1-4, ARG1 HRH1 130/4885HRH3 40/4885CYP1A2 1415/4885
US-20260118758-A1 SALT, ACID GENERATOR, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN RER1, MSR1, CBR1 HRH1 228/4885HRH3 99/4885CYP1A2 1755/4885
US-12624016-B2 Salt, acid generator, resist composition and method for producing resist pattern CLIC4, SCO2, H1-0 HRH1 100/4885HRH3 30/4885CYP1A2 2043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.