Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792272 | 0.89 | PDE10A (0.69) | PDE10ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL31694655 | 0.89 | PDE10A (0.69) | PDE10ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL10271340 | 0.77 | HRH4 (0.51) | PDE10AMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL17179175 | 0.77 | FGFR3 (0.47) | PDE10AMAPTSMN1; SMN2MEN1KMT2A | |
| Chlorobenzene SCHEMBL28001998 | 0.77 | CYSLTR1 (0.49) | PDE10ANPC1MAPTMEN1KMT2A | |
| SCHEMBL9971272 | 0.74 | PDE10A (0.77) | PDE10ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL2646721 | 0.74 | PDE10A (0.69) | PDE10ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL12066225 | 0.73 | PDE10A (1.00) | PDE10AMAPTMEN1KMT2A | |
| SCHEMBL19287901 | 0.72 | PDE10A (0.67) | PDE10AMAPTMEN1KMT2AHTT | |
| SCHEMBL7068584 | 0.71 | PDE10A (0.71) | PDE10ANPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529889-B | A kind of dehydration C- alkylations of heterocyclic methyl compound | 温州大学 | 2018-09-04 | — | — | CN | disclosed |
| CN-104529889-A | Dehydration C-alkylation method for heterocyclic methyl compound | UNIV WENZHOU | 2015-04-22 | — | — | CN | disclosed |