Chlorobenzene

Chlorobenzene

SCHEMBL28001998

CCc1ccc2ccccc2n1.Clc1ccccc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYSLTR1 Q9Y271 3/20 0.49
CYSLTR2 Q9NS75 2/20 0.49
CYP1A2 P05177 2/20 0.45
GPBAR1 Q8TDU6 3/20 0.42
PDE10A Q9Y233 1/20 0.42
CNR2 P34972 1/20 0.41
PTK2 Q05397 1/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALOX5AP P20292 1/20 0.41
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153778 0.89 CYSLTR1 (0.53) CYSLTR1CYSLTR2CYP1A2GPBAR1PDE10A
SCHEMBL29405396 0.89 CYSLTR1 (0.53) CYSLTR1CYSLTR2CYP1A2GPBAR1PDE10A
Iodide SCHEMBL28612904 0.87 CYSLTR1 (0.52) CYSLTR1CYSLTR2CYP1A2GPBAR1PDE10A
Ammonia Solution, Strong SCHEMBL28282609 0.87 CYSLTR1 (0.52) CYSLTR1CYSLTR2CYP1A2GPBAR1PDE10A
Hydrochloric Acid SCHEMBL28245253 0.87 CYSLTR1 (0.52) CYSLTR1CYSLTR2CYP1A2GPBAR1PDE10A
Hydrochloric Acid SCHEMBL5197438 0.87 CYSLTR1 (0.52) CYSLTR1CYSLTR2CYP1A2GPBAR1PDE10A
Hydrazine SCHEMBL28309928 0.85 CYSLTR1 (0.50) CYSLTR1CYSLTR2CYP1A2GPBAR1PDE10A
Quinoline SCHEMBL28296659 0.79 ALDH1A1 (0.61) CYSLTR1CYSLTR2CYP1A2GPBAR1PDE10A
Chlorobenzene SCHEMBL28002006 0.77 PDE10A (0.56) CYP1A2PDE10AMEN1GAAMAPT
SCHEMBL10546227 0.76 GPBAR1 (0.47) CYSLTR1CYSLTR2CYP1A2GPBAR1PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104529889-B A kind of dehydration C- alkylations of heterocyclic methyl compound 温州大学 2018-09-04 CN disclosed
CN-104529889-A Dehydration C-alkylation method for heterocyclic methyl compound UNIV WENZHOU 2015-04-22 CN disclosed