Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | POLB | P06746 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1277890 | 0.88 | MAPT (0.77) | MAPTPOLBMEN1KMT2ATDP1 | |
| SCHEMBL2911533 | 0.85 | MAPT (0.68) | MAPTPOLBMEN1KMT2ATDP1 | |
| SCHEMBL717794 | 0.83 | MAPT (0.71) | MAPTPOLBMEN1KMT2ATDP1 | |
| SCHEMBL16816933 | 0.83 | MAPT (0.76) | MAPTPOLBMEN1KMT2ATDP1 | |
| SCHEMBL7037581 | 0.82 | MAPT (0.68) | MAPTPOLBMEN1KMT2ATDP1 | |
| SCHEMBL737722 | 0.80 | MAPT (1.00) | MAPTPOLBMEN1KMT2ATDP1 | |
| SCHEMBL29409289 | 0.80 | MAPT (1.00) | MAPTPOLBMEN1KMT2ATDP1 | |
| SCHEMBL2774063 | 0.78 | MAPT (1.00) | MAPTPOLBMEN1KMT2ATDP1 | |
| SCHEMBL29655075 | 0.78 | MAPT (0.54) | MAPTPOLBMEN1KMT2ATDP1 | |
| SCHEMBL5952772 | 0.78 | TDP1 (0.79) | MAPTPOLBMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507473-A | Antiviral drug for treatment of arenavirus infection | SIGA TECHNOLOGIES INC | 2015-04-08 | — | — | CN | disclosed |