Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | EYA2 | O00167 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238927 | 0.82 | KDM7A (0.34) | KDM7APHF8KDM2ATDP1EYA2 | |
| SCHEMBL29068720 | 0.80 | PHF8 (0.39) | KDM7APHF8KDM2ATDP1EYA2 | |
| SCHEMBL13287140 | 0.78 | PHF8 (0.38) | KDM7APHF8KDM2ATDP1EYA2 | |
| SCHEMBL15131278 | 0.77 | LMNA (0.33) | KDM7APHF8KDM2ATDP1LMNA | |
| SCHEMBL27968686 | 0.75 | — | — | |
| SCHEMBL13401866 | 0.75 | TDP1 (0.38) | KDM7APHF8KDM2ATDP1EYA2 | |
| SCHEMBL8151293 | 0.73 | KDM7A (0.34) | KDM7APHF8KDM2ATDP1EYA2 | |
| SCHEMBL28002952 | 0.73 | CA12 (0.47) | KDM4ELMNAALOX15 | |
| SCHEMBL5723840 | 0.72 | — | — | |
| SCHEMBL1558594 | 0.71 | EPHX2 (0.34) | KDM7APHF8KDM2ATDP1EYA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829331-A | Method of producing pyrazino[2,1-c][1,2,4]triazine compound | 株式会社棱镜制药 | 2016-08-03 | — | — | CN | disclosed |
| CN-102046628-B | Alpha helix mimetics and methods relating thereto | PRISM BIOLAB CORP | 2015-04-15 | — | — | CN | disclosed |