Dibenzothiophene

Dibenzothiophene

SCHEMBL28003276

c1cc2sccc2s1.c1ccc2c(c1)sc1ccccc12

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.70
MAPT P10636 6/20 0.48
ALDH1A1 P00352 5/20 0.48
RAB9A P51151 3/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
ALOX15 P16050 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
POLB P06746 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.35
MCL1 Q07820 1/20 0.35
IKBKB O14920 1/20 0.35
LIMK1 P53667 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzothiophene SCHEMBL27960487 0.98 GPR3 (0.67) GPR3MAPTALDH1A1RAB9AHPGD
Dibenzothiophene SCHEMBL27977008 0.98 GPR3 (0.67) GPR3MAPTALDH1A1RAB9AHPGD
Dibenzothiophene SCHEMBL27856990 0.87 GPR3 (0.93) GPR3MAPTALDH1A1RAB9AHPGD
Dibenzothiophene SCHEMBL27960486 0.86 GPR3 (0.64) GPR3MAPTALDH1A1RAB9AHPGD
Dibenzothiophene SCHEMBL2561055 0.86 GPR3 (0.64) GPR3MAPTALDH1A1RAB9AHPGD
Dibenzothiophene SCHEMBL14659543 0.84 GPR3 (1.00) GPR3MAPTALDH1A1RAB9AHPGD
Dibenzothiophene SCHEMBL30167635 0.84 GPR3 (1.00) GPR3MAPTALDH1A1RAB9AHPGD
Dibenzothiophene SCHEMBL13294 0.84 GPR3 (1.00) GPR3MAPTALDH1A1RAB9AHPGD
SCHEMBL12446302 0.81 GPR3 (0.56) GPR3MAPTALDH1A1RAB9AHPGD
Dibenzothiophene SCHEMBL9934048 0.81 GPR3 (0.93) GPR3MAPTALDH1A1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104302622-A Phenacene compounds for organic electronics BASF SE 2015-01-21 CN disclosed