SCHEMBL28003455

SCHEMBL28003455

CC(=O)OC(C)(C)C/N=C/CC1CCCC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28003440 0.98 EPHX1 (0.32) GAAEPHX1
SCHEMBL27353237 0.74 GAA (0.38) GAAEPHX1
SCHEMBL2151537 0.73 EPHX1 (0.36) GAAEPHX1
SCHEMBL5153825 0.73 GAA (0.45) GAAEPHX1
SCHEMBL12895143 0.73 GAA (0.36) GAAEPHX1
SCHEMBL2151336 0.72 EPHX1 (0.38) GAAEPHX1
SCHEMBL22466309 0.71 GAA (0.44) GAAEPHX1
SCHEMBL28003454 0.71 GAA (0.32) GAA
SCHEMBL28817543 0.71 GAA (0.32) GAA
SCHEMBL28003446 0.71 GAA (0.32) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102159207-B Substituted pyrrolidine-2-carboxamides HOFFMANN LA ROCHE 2015-02-04 CN disclosed