Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12895143 | 0.98 | GAA (0.36) | GAATHRATHRBGRM2GRM3 | |
| SCHEMBL5153825 | 0.82 | GAA (0.45) | GAASMN1; SMN2HSD17B10HPGDMEN1 | |
| SCHEMBL22466309 | 0.81 | GAA (0.44) | GAASMN1; SMN2HSD17B10HPGDCTSS | |
| SCHEMBL9227258 | 0.81 | ALOX5 (0.39) | GRM2GRM3MMP1MMP9MMP13 | |
| SCHEMBL28546095 | 0.80 | GLI1 (0.32) | GAA | |
| SCHEMBL8733111 | 0.79 | THRA (0.35) | THRATHRBGRM2GRM3MMP1 | |
| SCHEMBL31352655 | 0.78 | NAAA (0.39) | GRM2GRM3HPGDMEN1MAPT | |
| SCHEMBL3248628 | 0.77 | THRA (0.44) | THRATHRBGRM2GRM3MMP1 | |
| SCHEMBL13162228 | 0.77 | PDK1 (0.36) | GAATHRATHRBGRM2GRM3 | |
| SCHEMBL20106634 | 0.75 | GAA (0.35) | GAAGRM2GRM3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031339-C | Heterocyclically substituted phenylacetic acid derivatives, processes for their preparation and their use in medicaments | BAYER AG (DE) | 1996-03-20 | — | — | CN | disclosed |
| CN-1066065-A | The phenylacetic acid derivatives of heterocyclic substituted and method for making thereof and pharmaceutical use | BAYER AG (DE) | 1992-11-11 | — | — | CN | disclosed |